PhD defense (Nov 2012)
Simon Tylsgaard Larsen, will defend his PhD thesis on “Thin film microelectrodes for electrochemical detection of neurotransmitters” on November 19. Examiners will be Professor Elisabeth M. J. Verpoorte, University of Groningen, Vice President, R&D, Sophion Bioscience A/S, and Professor Niels Bent Larsen, DTU Nanotech.
PolyNano paper included in IOPselect (Oct 2012)
The paper "Fabrication of combined-scale nano- and microfluidic polymer systems using a multilevel dry etching, electroplating and molding process" by Simone Tanzi, Peter Friis Østergaard, Marco Matteucci, Thomas Lehrmann Christiansen, Jiri Cech, Rodolphe Marie and Rafael Taboryski has been selected by the IOP editors to be included in IOPselect. Papers included in IOPselect fullfil one or more of the following requirements according to the editors:
- Substantial advances or significant breakthroughs
- A high degree of novelty
- Significant impact on future research
Talk: "Optofluidics 2012 and CHInano 2012" in Suzhou, Kina (September 2012)
Anders Kristensen, Optothermal Actuation in Nanofluidics
Abstract: The entropic confinement of DNA in nanofluidic devices – where the DNA is localized and streched but not tethered to a surface - is a powerful tool for manipulating single DNA molecules. In particular, measuring physical or genomic properties such as sequence mapping of single molecules is made possible by confining DNA in nanochannels and imaging by fluorescence microscopy. The ability to select and manipulate individual molecules on a chip is desirable for the development of a nanofluidic technology base for DNA analysis. We present an optothermal actuation scheme for nanofluidic DNA chips: A nanoimprinted polymer chip with a thin near-infrared absorber layer that enables light-induced local heating (LILH) of liquids inside micro- and nanochannels. An infrared laser spot and corresponding hot-spot could be scanned across the device. Large temperature gradients yield thermophoretic forces, which are used to manipulate and stretch individual DNA molecules confined in nanochannels. Light form a 785 nm laser diode was focused from the backside of the chip to a spot diameter down to 5 μm in the absorber layer, yielding a localized heating (Gaussian profile) and large temperature gradients in the liquid in the nanochannels. A laser power of 38 mW yielded a temperature of 40oC in the center of a 10 μm 1/e diameter. Flourescense microscopy was performed from the frontside.
PhD defense: Stephania Gasparin - Verification of Tolerance Chains in Micro Manufacturing
DTU Mechanical Engineering